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Moving to a new residence during the first three months of pregnancy is linked to a heightened risk of premature birth and low birthweight, as well as a slightly higher risk of a smaller-than-expected-size baby, according to new research from the 天美影视传媒 published online today in the .

Still, it鈥檚 too soon to raise warning flags.

“I don’t think we have enough information to make any specific recommendations about moving during pregnancy at this point, but I’m hopeful that our study will draw attention to moving as a risk factor worth investigating in more detail,” said , the lead author who conducted the research while at the UW School of Public Health.

Little is known about the potential health impact of a house move during pregnancy. To try to 聽rectify this, the researchers analyzed birth certificate data for babies born in Washington state between 2007 and 2014 to mothers who were 18 or older.

The researchers randomly selected 30,000 women who had moved during the first three months of pregnancy, known as the first trimester, and compared them with 120,000 randomly selected women of the same birth year, but who hadn鈥檛 moved during early pregnancy.

The first trimester was chosen because previous research has suggested that major stressors during early pregnancy have a greater impact on the health of the baby than those experienced later on in the pregnancy.

The final analysis included 28,011 women who had moved early in pregnancy and 112,451 who hadn鈥檛.

Women who moved early in pregnancy were likely to be younger, to be less educated, to have lower levels of household income and to have had other children than women who hadn鈥檛 moved. Researchers noted that this cohort also was more likely to be unmarried and to have smoked during their pregnancy.

These circumstances and behaviors are all聽potential risk factors for the outcomes the researchers were looking at: low birthweight; premature birth; and smaller鈥搕han-expected-size babies.

After taking account of these potentially influential factors, a house move during the first three months of pregnancy was associated with a 37% heightened risk of low birthweight and a 42% heightened risk of premature birth compared with those who didn鈥檛 move during this period.

A house move in the first trimester was also associated with a slightly increased risk of giving birth to a smaller-than-expected-size baby.

These differences were seen across women in all social and economic strata that was analyzed.

As an observational study, researchers can鈥檛 establish cause.聽The researchers were not able to explore the potential reasons behind their findings, but interruptions to health care, the physical strain of moving, disruptions to social support systems, and a biological stress reaction may all be possible triggers, according to the report.

Although the study included a large number of women, the researchers weren鈥檛 able to establish the reasons for the participants鈥 moves or whether they moved into more or less desirable areas, which may have influenced the results.

鈥淒espite these limitations, our results yield important insights regarding moving during pregnancy,鈥 the researchers write in the report. 鈥淩egardless of whether the negative impact of moving is driven by the stress from the move itself, stressful situations leading to a move, or disruption of care because of the move, asking patients about plans to move and using that as an opportunity to counsel patients on stress-mitigating techniques and care continuity may be beneficial.鈥

Co-authors on the study include graduate students Amanda Mancenido, Divya Patil and Seth Rowley, as well as faculty Alyson Littman and Jack Goldberg, all of the UW.

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Reach Bond at jcbond@uw.edu.